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A Defiance, Serious Skincare's original anti-aging collection features anti-aging retinol and retinyl palmitate - the most effective forms of vitamin A, are nanofied and time released for a steady, sustained delivery into the skin. The products in the A Defiance line provide unprecedented results against the first signs of age and sun damage on the skin. This is an overnight beauty anti-aging gel, applied to the skin at night to help keep the skin looking more refreshed.

Overnight Retinol Renewal Gel Benefits

  • For most skin types
  • Multi-Tasking Overnight Reveal is clinically shown to start reducing the look of wrinkles overnight and over 28 days of continued use
  • Clinically shown to help increase the appearance of skin's brightness in 28 nights of use
  • This multi-tasking Renewal Gel addresses and improves the look of skin's smoothness
  • Features 9 different AHA sources: lactic acid, glycolic acid, mandelic acid, extract of: bilberry, sugar cane, sugar maple, orange, lemon, and peach
  • No apparent fragrance
  • Gel-like liquid
  • Glass bottle with pump dispenser and cap
  • Made in the USA

Please see the Usage & Ingredients tab for how to use and ingredient information.

For questions about product, please contact the Serious Skincare Customer Support line: 1-800-540-8662.

What is a Serum?
Deciding to use a serum can depend on various factors including skin type, age or degree of damage. They are able to effectively absorb onto the skin, delivering active ingredients for maximum benefit. Depending on ingredients, serums contain anti-aging properties that help to firm, tighten, provide anti-oxidants, re-texturize, or address the signs of aging. If you decide to use a serum with your moisturizer, select one with the ingredients or benefits associated with the concerns you wish to address.

Aging skin may have any combination of wrinkles, sagging or slack skin around the jowls, chin, cheeks and jawline. It may also have evidence of sun damage (photo damage/hyperpigmentation) in the form of spots or leathery texture. The skin may also feel tight and dry. If you tend to have dry skin, you will need moisturizing products that nourish, so you will want to find protective and restorative products. Achieving a moisture balance with the right pH is key.

Daily Skin Care Regimen
Begin with a very mild soap, possibly cream based. Since skin can be acidic, the alkaline in soap can easily disturb the delicate pH balance. Also, make sure the soap does not contain harsh chemicals which will also remove the acid mantel and cause further dryness. Choose a toner that soothes and nourishes your skin. It should refresh with a hint of moisture - a low or no alcohol formulation is recommended to prevent over drying the skin.

A daily moisturizing routine is essential to aging skin. After washing skin, pat it dry and begin with a serum to enhance moisture, then apply a day moisturizer. Try to use a day cream with an SPF An evening ritual can include a serum application and a heavier moisturizer. Eye creams and serums are recommended for the delicate area around the eyes that are subject to fine lines and wrinkles.

Weekly Skin Care Routine
Use an extremely mild exfoliator in order to expose fresh skin and allow products to absorb. This will maximize the effectiveness of your skin care products. A moisture-enhancing mask that you put on and wipe off will moisturize and plump skin that may be dry and dehydrated.

Product Recommendations:

  • Makeup remover
  • Cleanser, mild or cream based
  • Toner (low or no alcohol)
  • Morning moisturizer with SPF
  • Evening moisturizer
  • Eye moisturizer
  • Serum
  • Mild exfoliant
  • Moisture enhancing mask

    Key Ingredients for Aging Skin:
    Hyalauronic acid, Manuka Honey, Evening Primrose Oil, Borage Oil, Almond Oil, Apricot Oil, Algae Extract, Caffeine, Green Tea, White Tea, Idebenone, Vitamin C, Vitamin E, Grape Seed Extract, Alpha Hydroxy Acids, DMAE, Retinol, Aloe Vera, Borage Seed Oil, Ceramide, Cocoa Butter, Evening Primrose Oil, Glycolic Acid, Jojoba Oil, Lactic Acid, Shea Butter, Pycnogenol Cucumber, Copper Peptide, Coenzyme Q10 (Ubiquinone), Hydrolyzed Wheat Protein

  • Enjoy regular arrivals of your favorite products, without the hassle of reordering. Choose Subscription on an item, and you'll receive regularly scheduled deliveries. Price is locked in at the price you pay today. It's simple, easy, and cancellable at any time.

    Subscription-Every 30 Days- Serious Skincare Anti-Aging Overnight Retinol Renewal Gel 1oz

    Frequency: Every 30 (days) - Program Shipment Price: $49.95
    Delivery Item Quantity Description
    1 315-675 1

    About the Collection
    Serious Skincare was founded over two decades ago by Jennifer Flavin-Stallone to address acne and problematic skin. It has since evolved into the premiere skincare and beauty brand with a full line of science-based products that address a myriad of skincare and cosmetic issues. By using potent quantities of high-end, anti-aging ingredients, acne fighting acids and skin softening moisturizers, Serious Skincare provides innovative, highly effective and targeted treatments for women and men.

    Serious Skincare
    For whatever skin you’re in

    About the Experts

    Jennifer Flavin-StalloneAbout Jennifer Flavin-Stallone
    In her early 20s Jennifer Flavin-Stallone was modeling and battling acne – nothing worked, until she heard about a little skincare company in California called Serious Skincare. It worked miracles on her acne issues and so she joined forces with founder, Lisa Stock, to bring Serious Skincare to home shopping 25 years ago and help develop it into one of the largest online beauty brands. As Jennifer’s skincare needs have evolved, so has the brand. She has been a driving force behind the innovative products released by Serious Skincare over the years, the most recent being the debut of TAKE2, a product line developed specifically for age 50+ skin.





    Cecilia StockAbout Cecilia Stock
    Cecilia Stock is the daughter of co-founder Lesa Stock, and the inspiration for Serious Skincare’s very first product. Since then, Cecilia has become an accomplished acne and anti-aging specialist and esthetician, working with clients around the world. Her greatest accomplishment is helping acne clients achieve greater self-confidence.







    John PinocciAbout John Pinocci
    John Pinocci has nearly 4 decades of retail experience, with heavy focus on beauty and fragrance categories. In 1994, he helped launch Serious Skincare to national TV retailing and went on to join the company officially in 1996, working with Jennifer to grow Serious Skincare into a beauty powerhouse. Known to many customers as “Serious John,” he’s typically behind the scenes and the voice of the service and support center.

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    How To Use

    Apply a thin layer to freshly clean, healthy skin every night. In case of direct eye contact, rinse thoroughly with water. Stop use if rash or irritation occurs. Do not use on damaged skin. Keep in a dry, cool place and out of reach of children. For external use only.

    Average Days of Supply: 30.

    Ingredients

    Aqua (Water), Glycerin, Glycolic Acid, Sodium Hydroxide,Lactic Acid, Cyclopentasiloxane, Carbomer, Panthenol,Mandelic Acid, Vaccinium Myrtillus Fruit Extract, Saccharum Officinarum (Sugar Cane) Extract, Citrus Limon (Lemon) Fruit Extract, Citrus Aurantium Dulcis (Orange) Fruit Extract, Retinol, Retinyl Palmitate, Helianthus Annuus (Sunflower) Seed Oil, Acer Saccharum (Sugar Maple) Extract, Zea Mays (Corn) Germ Oil,Tocopherol, Beta-Carotene, Lecithin, Prunus Persica (Peach) Fruit Extract, Xanthan Gum, Dimethiconol, Caprylic/Capric Glycerides, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dipotassium Glycyrrhizate, Disodium Edta, Polymethyl Methacrylate, Bht, Triethanolamine, Tricaprylin, Alcohol, Ethylhexylglycerin, Parfum (Fragrance), Phenoxyethanol.